pentobarbital will minimize the extent or impact of levamlodipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the level or outcome of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with robust CYP3A4 inducers can result in diminished serum concentrati